261 results found in 0.239 second.
PDF Drive is a search engine designed to find PDF files. As of today we have 54,520,136 ebooks for you to download for free.
Arts Biographies Business Children Computers Education Gay & Lesbian Health History Law Literature Medical Religion Science Sports
Page count: Sort by: Search in:
Pages: 131
Size: 717 KB
Year: 2007
Price: Free

Novel Prodrug Structures for Improved Drug Delivery

Oct 27, 2007 pharmaceutical properties of novel prodrug structures, including aqueous solubility
Pages: 16
Size: 292 KB
Year: 2008
Price: Free

Prodrug Designing of NSAIDs - ResearchGate

The prodrug designing is one of the several strategies used to overcome this In this paper, a
Pages: 14
Size: 167 KB
Year: 2007
Price: Free

A Water-Soluble Propofol Prodrug

pofol is cleaved by alkaline phosphatase to phosphate, formaldehyde and propofol. Formaldehyde is rapidly metabolised to formate. Although a formate 
Pages: 4
Size: 1006 KB
Year: 2005
Price: Free

Prodrug activation via catalytic antibodies

Proc. Natl. Acad. Sci. USA. Vol. 90, pp. 5337-5340, June 1993. Chemistry. Prodrug activation via
Pages: 198
Size: 9.39 MB
Year: 2001
Price: Free

A STUDY OF DT-DIAPHORASE AS A PRODRUG-ACTIVATING

It has a dual role both as a prodrug-activating enzyme and as a protector in on his insighrfùl
Pages: 125
Size: 2.84 MB
Year: 2011
Price: Free

optimizing the enzyme/prodrug axis of suicide gene therapy using

prodrug must elicit a robust bystander effect, preferably by intracellular . dFdCDP acts as a
Pages: 27
Size: 299 KB
Year: 2011
Price: Free

ADC and prodrug linker - Annova Chem Inc.

Annova Chem Product - ADCs and Prodrug Linker Catalog_# CAS_RN Chemical_Name FW Formula LC0001
Pages: 29
Size: 165 KB
Year: 2008
Price: Free

Prodrugs for Amines

Mar 3, 2008 amide prodrugs that release, in vivo, the parent amine [21] A group at the Pasteur Institute later speculated that the azo link might not be 
Pages: 23
Size: 292 KB
Year: 2010
Price: Free

Prodrug Approach for Increasing Cellular Glutathione - MDPI.com

Mar 3, 2010 Once intracellular GSH is produced, some of it is delivered to specific to GSH by NADPH-dependent glutathione reductase (GR) (Figure 1).
Pages: 15
Size: 789 KB
Year: 2008
Price: Free

Site-Specific Prodrug Release Using Visible Light

Site-Specific Prodrug Release Using . Visible Light. Michael Y. Jiang and David Dolphin* J. Am
Pages: 12
Size: 148 KB
Year: 2001
Price: Free

Strategies for Enzyme/Prodrug Cancer Therapy

Minireview Strategies for Enzyme/Prodrug Cancer Therapy1 Guang Xu and Howard L. McLeod2 Washington
Pages: 11
Size: 450 KB
Year: 2011
Price: Free

Glucuronidation of Anticancer Prodrug PR-104A: Species

clinical trial as a hypoxia- and aldo-keto reductase 1C3. (AKR1C3)-activated prodrug . tive
Pages: 9
Size: 3.83 MB
Year: 2011
Price: Free

Acid-Activatable Prodrug Nanogels for Efficient Intracellular

release in cancer cells. DOX prodrugs with drug grafting contents of 3.9, 5.7, and 11.7 wt % (denoted as prodrugs 1, 2, and 3, respectively) were
Pages: 9
Size: 141 KB
Year: 2005
Price: Free

Prodrug-Oriented Molecular Design of Neonicotinoids: Preparation

Prodrug-Oriented Molecular Design of Neonicotinoids: Preparation of Imidacloprid-Related 5,5
Pages: 9
Size: 199 KB
Year: 2001
Price: Free

Glucuronidation of Prodrug Reactive Site - Clinical Chemistry

clude prodrug forms of platelet-activating factor antago- nists (1), antiviral .. cleotide
Pages: 7
Size: 302 KB
Year: 2005
Price: Free

BETAMETHASONE PHARMACOKINETICS AFTER TWO PRODRUG FORMULATIONS IN

BETAMETHASONE PHARMACOKINETICS AFTER TWO PRODRUG FORMULATIONS IN SHEEP: IMPLICATIONS FOR ANTENATAL
Pages: 7
Size: 967 KB
Year: 2005
Price: Free

Phase IStudy oftheOrally Administered Butyrate Prodrug, Tributyrin

Butyrates induce reversible growth inhibition orterminal differentiation inawide variety ofcell lines vitro (7.8).They have produced cell death incertain human
Pages: 8
Size: 243 KB
Year: 2004
Price: Free

camptothecin prodrugs

doi:10.1016/j.bmc.2004.01.039. Bioorganic & Medicinal Chemistry 12 (2004) Π– Π. Keywords: Prodrug
Pages: 2
Size: 106 KB
Year: 2001
Price: Free

Prodrug Metabolites: Implications for Therapeutic Drug Monitoring

Prodrug Metabolites: Implications for Therapeutic Drug Monitoring Prodrugs are analogs of active
Pages: 2
Size: 2.53 MB
Year: 2011
Price: Free

Prodrug form for improved solubility & bioavailability of

Prodrug form for improved solubility & bioavailability of therapeutic agents Technology Offering
Pages: 2
Size: 49 KB
Year: 2012
Price: Free

Site-Specific Prodrug Release Using Visible Light

backbone are barely changed as the photooxygenation took place Scheme 1. General Diagram of Drug Incorporation and Release Scheme 2.
Pages: 250
Size: 6.91 MB
Year: 2012
Price: Free

Synthesis and evaluation of dopaminergic prodrugs designed for

prodrugs designed for transdermal iontophoretic drug . of this thesis mainly concern DA D1 and DA D2 agonism and its clinical applications. Therefore, DA 
Pages: 31
Size: 168 KB
Year: 2007
Price: Free

Exploitation of Bile Acid Transport Systems in Prodrug - MDPI.com

Aug 16, 2007 The traditional prodrug approach aims to mask undesirable drug nutrient transport
Pages: 26
Size: 725 KB
Year: 2012
Price: Free

Title: Human carboxylesterase 2 hydrolyzes the prodrug of

Running title: Hydrolysis of the prodrug of gemcitabine, LY2334737. Key words: via slow
Pages: 25
Size: 456 KB
Year: 2011
Price: Free

Aminolevulinic Acid (ALA) as a Prodrug in Photodynamic Therapy

5-aminolevulinic acid based photodynamic therapy in WHO I meningioma cells corresponds to ferrochelatase activity. Photochem. Photobiol. 2011, 87, 235-241.
Pages: 24
Size: 8 MB
Year: 2012
Price: Free

HCV Nucleoside Prodrug Design and their Potencies - Informed

HCV Nucleoside Prodrug. Design and their Potencies. Steven J. Coats. Senior Director of Chemistry
Pages: 542
Size: 8.69 MB
Year: 2013
Price: Free

I-MAK's Pre-Grant Opposition to the prodrug application (with exhibits)

Jul 29, 2013 Exhibit 2 - Statement on a Nonproprietary Name Adopted by the USAN Council for Sofosbuvir. 29-30. 4. Exhibit 3 - Valentino Stella, Prodrugs 
Pages: 18
Size: 652 KB
Year: 2006
Price: Free

Developing a Beta-Lapachone Prodrug for Therapy Against NQ01

calcium store release as pretreatment with the intracellular calcium chelator . DT-diaphorase and cytochrome B5 reductase in human lung and breast tumours.
Pages: 16
Size: 292 KB
Year: 2008
Price: Free

124 Mini-Reviews in Medicinal Chemistry Prodrug Designing of NSAIDs

prodrugs of ibuprofen and naproxen were synthesized and biologically evaluated by Shanbhag et al. [33]. The ulcero-genicity of the prodrugs 11a, 12a, 11h, and 12d was
Pages: 14
Size: 160 KB
Year: 2013
Price: Free

Hypoxia Is An Attractive Target for The Bioreductive Prodrug in

Jul 12, 2013 reduced by intracellular oxidoreductases in an oxygen-sensitive manner . anoxia in vitro, with the one-electron reductase POR appearing to